A team of researchers led by Duke University, the University of California San Francisco, and the Beckman Research Institute ...

Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor ...

Nxera Pharma has entered a collaboration and licensing agreement with Antiverse to design antibodies for GPCRs.

The structures of engineered versions of these receptors finally provide much-needed answers to this fundamental question. ORs are members of the superfamily of membrane-bound proteins known as G ...

Introduction: TGR5 belongs to G-protein coupled receptor family, that mediates bile acid signaling. Activation of TGR5 by bile acids triggers intestinal glucagon-like peptide-1 secretion, whereby ...

In this article, we take a look at eight biotechs that have acquired funding in recent years to fortify their GPCR-focused ...

Researchers in biology and medicine have long dreamed of controlling the activities of cells without, for example, having to ...

Nxera Pharma & Antiverse collaborate to design novel GPCR-targeted antibody therapeutics using generative AI: Tokyo, Japan Wednesday, November 6, 2024, 13:00 Hrs [IST] Nxera Pharm ...

With their unique structure, nanodiscs improve drug delivery and vaccine development, stabilizing membrane proteins for effective therapeutic applications.

The human gut is home to helpful microbes, called the microbiota, who produce molecules known as metabolites. These ...