The epithelial–mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and ...

【导读】肺腺癌（LUAD）是肺癌的主要亚型。LUAD患者的预后不佳主要是由于转移所致。ADAMTS16是ADAMTS家族的重要成员，参与肿瘤进展。然而，其在LUAD中的作用和调节机制尚未被研究。11月17日，华中科技大学刘博研究团队在期刊《Cell ...

The developmental program Epithelial-Mesenchymal Transition (EMT) is frequently re-activated in metastatic and recurrent tumors. Our work provided a conceptual understanding depicting a causal role ...

Proliferative dysfunctions on the eye surface represent a significant area of concern within ophthalmology, characterized by ...

Hepatocellular carcinoma (HCC) is a significant global health concern, particularly in regions like the Asia-Pacific, where ...

More information: Khalil Kass Youssef et al, Two distinct epithelial-to-mesenchymal transition programs control invasion and ...

The transcriptomic analysis also revealed the activation of pathways that promoted tumor development, such as epithelial-to-mesenchymal transition pathways.