Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of ...

Speak with your doctor or pharmacist if you have any concerns about potential drug interactions. ACE inhibitors are also not as effective in treating chronic kidney disease in people who smoke.

and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme called Matrix Metallopeptidase 7 (MMP7).

Metoprolol can interact with several types of medications, including certain blood pressure drugs, monoamine oxidase ...

A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by ...

Hypotension is not a specific side effect with ACE inhibitors; rather, it is a broadening of the physiologic action of these drugs that occurs most commonly when a patient becomes volume contracted.

Drawing inferences from observational data with possible confounding Heart failure is increasing in prevalence and is a major cause of morbidity and mortality worldwide,1 with prevalence ranging from ...

There remains an art as much as a science to the use of these drugs. The science behind ACE inhibitor use is well accepted, the art, however, is a work in progress, with many subtleties to use ...

Celcuity's lead asset, Gedatolisib, is a dual PI3K/mTOR inhibitor targeting various cancers, currently in multiple Phase 3 ...

The glaucoma drug methazolamide removed tau build-up and lessened signs of dementia in genetically-engineered zebrafish and mice.

Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.