Drawing inferences from observational data with possible confounding Heart failure is increasing in prevalence and is a major cause of morbidity and mortality worldwide,1 with prevalence ranging from ...

Celcuity's lead asset, Gedatolisib, is a dual PI3K/mTOR inhibitor targeting various cancers, currently in multiple Phase 3 ...

Angiotensin-converting enzyme (ACE) inhibitors are a class of medication used to treat and manage heart-related conditions such as high blood pressure, heart failure, and kidney issues. These drugs ...

Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of ...

EpiVario, Inc. has announced that the United States Patent and Trademark Office has granted them US Patent No. 12,077,527, ...

Eating licorice regularly, in large quantities or with certain medications can cause serious side effects. But why is that?

The glaucoma drug methazolamide removed tau build-up and lessened signs of dementia in genetically-engineered zebrafish and mice.

Each year, more than 3 million people are diagnosed with cancers driven by mutations in three RAS-family genes: KRAS, NRAS, ...

Glaucoma drug methazolamide shows potential in fighting neurodegenerative diseases, offering new hope for treating conditions like Alzheimer's and Parkinson's.

The drug works by essentially forcing our cells to "spit out" dangerous protein clumps involved in Alzheimer's.

A new study shows that a common glaucoma drug cleared tau build-up and reduced signs of neurodegenerative disease in zebrafish and mice.