DNA and RNA are nucleic acids found in the nucleus of the cells in every living organism. Both nucleic acids participate in the coding, decoding, regulation and expression of genes. Application of ...

The methods, RNA-overhang cloning (ROC) and DNA-overhang cloning (DOC), generate polymerase chain reaction (PCR) 1 products composed of double-stranded (ds) DNA flanked by single-stranded (ss ...

Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...

Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, ...

Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is ...

StitchR, a new gene therapy technique, delivers large genes in two parts to treat muscular dystrophies by restoring critical proteins in animal models.

A new technology that delivers two halves of a gene separately could enable gene therapy treatments of muscular dystrophies.

This target centers on RNA regulation, which, when disrupted in humans, is often linked to neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, as well as many types of cancer.

Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...