Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...
(h-l) RNAseq based transcript abundance levels for specific genes involved in the HR DNA repair pathway (Wilcoxon rank test p-values shown). (a) Genes downregulated by acute CDK12 inhibition skew ...