Johns Hopkins University School of Medicine and Johns Hopkins Kimmel Cancer Center researchers Stephen Baylin, M.D., and Andrew Feinberg, M.D., were ...
As an oncometabolite, R-2-HG induces malignant transformation of glial progenitor cells by altering the chromatin structure (through broad DNA and histone hypermethylation) and disrupting the ...
DNA methylation is a fundamental modification characterized by the addition of a ... By analyzing 571 PTC samples from The Cancer Genome Atlas (TCGA), the researchers found that patients with TERT ...
It started with a finger bone found in a cave in the Altai mountains in Siberia in the late 2000s. Thanks to advances in DNA analysis, this was all that was required for scientists to be able to ...
Human genome sequencing methods. (NIH) These overlooked genes have been hiding away in regions of our DNA thought not to code for proteins. These regions were once dismissed as 'junk DNA' but it turns ...
Their engineered cells can insert distinctive bits of genetic material into their DNA. As the cells divide, those genetic bits turn into distinctive bar codes. The technology is also allowing ...