For most proteins, these two opposing processes are dynamically balanced during the cell cycle, holding each protein at a constant (steady state) level. For some proteins (for example, cyclins ...

Further investigation is required to clarify this putative cell-cycle connection. Interestingly, the other key players of the RB–E2F pathway, such as D-type cyclins, CDK-inhibitory proteins (ICK ...

Cyclins and cyclin-dependent kinases (CDKs) regulate the activity of E2F and Rb to drive cell cycle progression. Disrupting this interaction has shown lethality in cancer cells harboring alterations ...

Gilk, Rajendra Angara and Arif Sadi. The cover shows a 3D rendering of a Z-stack image using the Alpha-blending algorithm in the NIS elements software illustrating the localization of the secreted ...

We aim to review research in all areas of cell biology, including but not limited to studies on cell cycle, cell polarity and fate, nuclear and chromosome organization and segregation/division, signal ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Don't want to be left out in the cold when it comes to cell signal? Try these tips and tricks. Nelson Aguilar is an LA-based tech how-to writer and graduate of UCLA. With more than a decade of ...

Researchers are exploring the world’s first virtual human cell, an AI-powered model designed to simulate the complex behavior of human biomolecules, cells, and tissues. Credit: Emma Lundberg Recent ...

These terminal sugar residues on glycoproteins and glycolipids modulate key cellular processes such as immune evasion, cell adhesion, and migration. Aberrant sialylation is driven by overexpression of ...