Structures of ApoB100 show LDL receptor contact points ...

Protein contact dermatitis is an allergic skin reaction induced principally by proteins of either animal or plant origin. The clinical presentation is that of a chronic dermatitis, and it is often ...

Cross-linking mass spectrometry (XL-MS) can reveal protein-protein interactions (PPIs) and the structural information of their binding interfaces in native biological systems (Liu et al, 2017; ...

Development of methods for time-resolved structural studies using synchrotron and XFEL radiation, applied to study membrane-bound energy converting enzymes of the cell. Structure-based drug design to ...

The story so far: The 2024 Nobel Prize for chemistry was jointly awarded to David Baker for his work on computational protein design and to Demis Hassabis and John Jumper for developing ...

A transformer network trained to predict end-to-end single sequence protein structure as a set of angles given amino acid sequences.

This valuable study presents a thorough analysis of protein abundance changes caused by amino acid substitutions, using structural context to improve predictive accuracy. By deriving substitution ...

Compared to the sole use of amino acid sequences or protein structure data, the proposed method took a multi-level feature fusion ... Therefore, 5-fold cross-validation was used to conduct ablation ...

This innovative tool analyzes biomarkers that can induce 3D structural ... protein quantitative trait loci) to identify disease-related proteins. MR-SPI is a powerful tool designed for studies ...

"Think of it like a super detailed map showing how different proteins in a cell are connected," Coskun said. The iseqPLA can examine 47 protein interactions in a single sample, which saves a lot ...