Recombinant methods, combined with structure-based design, have enabled the development of “synthetic” antibody libraries with entirely man-made binding sites 10.
Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with each ...
Although fewer antibody fragments have entered the clinic ... In addition, the variety of molecular types of fragments has increased over time, with Fab the only fragment type first studied ...
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