In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting β-catenin, a historically 'undruggable' protein, in just two months. This ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

RiDYMO® has been successfully employed in various drug discovery programs, including the development of small molecule ...

The intracellular signalling cascade of IL-33 might share many of the features of canonical Toll-like receptor ... potential of targeting this pathway in the prevention of cardiac fibrosis and ...

Path of Exile 2's upcoming patch will introduce new gameplay features, such as fast-travel points within areas, for easier exploration. The patch will also reduce the cost of respeccing Passive ...

GameSpot may get a commission from retail offers. Path of Exile 2 is finally out in early access and while only half of the eventual content is in the game right now, there are still hours of ...

Mainstreaming the below protection principles listed in no particular order of importance will allow to maximize the protection impact of complementary pathways. Complementary pathways help enhance ...

In 2024, Canada launched several new pathways to permanent residence and has made major changes to existing pathways. The below table showcases these updates for a clearer overview. Francophone ...

Researchers from Max Planck Florida Institute for Neuroscience have discovered a new pathway to forming long-term memories in the brain. Their work suggests that long-term memory can form ...

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States Life Science Institute, University of Michigan, Ann Arbor, Michigan 48109 ...