Lactylation is a reversible, covalent, post-translational modification of proteins. It occurs exclusively on lysine residues, where it influences protein structure, stability, localization, and ...
Several mutations affecting β-amyloid, either to APP 1,2,3 ... including the hippocampus. LTP is a model of such use-dependent enhancement in synaptic efficacy, and can be induced by activating ...
For example, certain tumour cell lines may serve as cancer models, and transgenic mice that express human beta-amyloid protein may serve as animal models of Alzheimer’s disease.
Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- ...
TaxDiff proposes a taxonomic-guided framework that fits all diffusion-based protein design models. We also propose the patchify attention mechanism for better protein design. Experiments demonstrate ...
thh.nhs.uk The amyloidoses are a group of diseases in which amyloid, a proteinaceous substance, deposits in one or more organs. As many as 23 different precursor proteins to the formation of amyloid ...
Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and ...