Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that ...

For example, certain tumour cell lines may serve as cancer models, and transgenic mice that express human beta-amyloid protein may serve as animal models of Alzheimer’s disease.

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- ...

TaxDiff proposes a taxonomic-guided framework that fits all diffusion-based protein design models. We also propose the patchify attention mechanism for better protein design. Experiments demonstrate ...

Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live ...

Raul Ruiz, director of FIU’s Bar Preparation Program, examined the theory, design, implementation and evaluation of what makes successful prep programs. He found LSAT and GPA aren’t reliable crystal ...

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of ...

To address these limitations, we propose a novel deep learning framework, named DeepFMB, which incorporates multi-type biological knowledge. DeepFMB leverages a pre-trained protein language model to ...