Major Finding: Alveolar macrophages (AM) induce dormancy in early disseminated cancer cells (DCC) in the lung. Concept: TGF-β2-TGF-βRIII signaling mediates DCC dormancy and is subverted during ...
Division of Genome Morphology, Department of Functional, Morphological and Regulatory Science, Faculty of Medicine, Tottori University, Yonago, Japan. Alveolar macrophages (AM) are a main population ...
A study was undertaken to determine whether relative CS insensitivity is present in alveolar macrophages from patients with severe asthma and its association with p38 mitogen-activated protein kinase ...
Other macrophage models have been developed but lack certain features unique to alveolar macrophages. The AML model solves both issues by starting with a simple blood draw from donors.
A study utilizing alveolar macrophage-like (AML) cells revealed that tumor necrosis factor (TNF) is critical for fighting tuberculosis but not other infections. The findings challenge existing beliefs ...