Epigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight ...

Adipose tissue changes during the day. It expresses clock genes that oscillate accurately and independently of the supraquiasmatic nucleus in adipose tissue explants. Nutrigenetics and ...

The hypothalamus integrates neurohormonal signaling from gut and adipose tissue. Specific hypothalamic nuclei, including the dorsomedial nucleus (DMN), paraventricular nucleus (PVN) and ...

Obesity creates lasting epigenetic changes in fat cells, making weight regain easier. Early prevention is key, as these ...

The study identifies the adhesion G-protein-coupled receptor A3 (ADGRA3) as a potential target for activating adaptive thermogenesis in white and brown adipose tissue, providing valuable information ...

Anyone who has ever tried to get rid of a few extra kilos knows the frustration: the weight drops initially, only to be back ...

Scientists have uncovered a new neuron type, BNC2, which acts quickly to counter hunger-promoting neurons, potentially ...

引言肥胖不只是一个简单的体重增加问题，更是一个牵涉广泛的代谢失调和慢性疾病的复杂现象。在过去的几十年中，全球肥胖率不断上升，使其成为威胁公众健康的主要问题之一。尽管许多人通过严格的饮食控制、运动干预、药物治疗，甚至减重手术成功减轻了体重，然而，随之而 ...

ETH Zurich researchers have identified an epigenetic memory in fat cells that drives the yo-yo effect after weight loss.

Researchers have discovered a mechanism behind the yo-yo effect: fat cells have a memory that is based on epigenetics.