Laboratory of Physical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece Theoretical and Physical Chemistry Institute ...

Angiotensin II binding to AT1 receptors promotes synthesis of transforming growth factor β1 (TGF-β1), which leads to increased protein kinase activity and initiates a cascade of phosphorylation ...

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

and angiotensin II subtype 1 (AT1) receptors, which are associated with progression of kidney disease. It's in late-stage development for IgA nephropathy and focal segmental glomerulosclerosis ...

15 19 Finally, the initial dosing of candesartan at 4 mg two times per day may have been insufficient to obtain sufficient AT1 receptor blockade, although our algorithm was designed to safely maximise ...

The angiotensin II receptor blockers (ARBs), are highly selective for the AT 1 subtype and will block the effects of angiotensin II on peripheral vessels. Several short-and long-term studies have ...

Toll-like receptors (TLRs) and their signalling pathways have therapeutic potential for the treatment of inflammation, cancer, infection, allergy and autoimmunity. The elucidation of the structure ...

Water and sodium retention during severe hypothyroidism create a state of volume depletion, low extracellular fluid osmolality and increased water retention. The hypothyroid population is ...

Contrary to the belief that the path to sustainable development is increasingly out of reach, the results show that humankind has a variety of pathways to depart from its current unsustainable ...