Not only can this type of assay provide information about whether gene expression changes are accompanied by chromatin remodeling, but it can also show where remodeling is taking place.
Instead, the chromatin remodeling complex SWR1 catalyzes an ... cells the capability to exert complex levels of control over gene expression. As described throughout this article, chromatin ...
Major changes in gene expression underlie changes in cell state, including cell growth and a stress-resistant state called quiescence. Our scientists study how the organization of our chromatin - the ...
In a groundbreaking study, scientists have discovered a way to manipulate the very fabric of life by using light to reshape ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence ... less condensed and packages regions that are much more accessible to ...
and their work to investigate and design chromatin-based systems for controlling gene expression in cancer. Her lab’s approach, which they call “macrogenomic engineering,” uses histone-binding protein ...
We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a transcription factor did not change how much of the transcription factor protein was expressed but determined the location ...
Understanding how transcription factors navigate chromatin could enable scientists ... bind to specific DNA sequences to regulate gene expression, directing cells to differentiate into specific ...