You have full access to this article via your institution. To test whether nuclear cloning could be used to generate transgenic mice with targeted insertions, we integrated a tet-transactivator ...

To mature them and induce meiosis, Kono's team had to transfer them into an enucleated oocyte from a wild-type mouse. With the haploid genome of the mutant oocyte in hand, they were finally ready ...

In psychiatric conditions like autism spectrum disorder and schizophrenia, differences in social behavior correlate with ...

A study published in Molecular Psychiatry found that brain volume changes correlate with social behavior differences in ...

The Tbx1 gene influences brain volume and social behavior in autism and schizophrenia, with its deficiency linked to amygdala ...

A study published in October 2024 in the journal Molecular Psychiatry found that brain volume changes correlate with social ...

Chimeric mice derived from complete Salhel-Sox-I iPSC lines, displaying black spots on their fur and black eyes (arrows), contrasting with a wild-type mouse with white fur and red eyes. The team thus ...

Complete SAD/MAD data from the Phase 1 trial of DISC-3405 in healthy volunteers were presented. In the SAD portion of this trial, healthy males and females ages 18 to 65 were given a single dose of ...

Scientists from Leiden University Medical Centre in the Netherlands filmed wild mice using an outdoor wheel for three years to analyse their behaviour They found the behaviour is natural even if ...

THΔper mice and wild-type littermates were fed either a regular chow diet or a high-fat diet (HFD) for varying durations to ...