Although some amyloidosis diseases, for example TTR amyloidosis, are caused by the aggregation of a single type of protein, other amyloid diseases are typically characterised by the build-up of ...
and AA (serum amyloid A) types. These two forms require different treatment strategies, and reliable differentiation between types is, therefore, clinically important. Satoskar and co-workers have ...
Moreover, the study found that the drugs targeted different types of amyloid, with the BACE inhibitor removing diffuse deposits of the protein while the antibody zeroed in in dense or 'cored' plaques.
Primary (AL) amyloidosis is the most prevalent type of systemic amyloidosis, and management of this disease has evolved through the years from supportive care to aggressive treatments that include ...
This is a highly conserved invariant plasma glycoprotein that, as a result of specific calcium-dependent binding to all types of amyloid fibril, becomes highly concentrated in amyloid deposits.
Amyloidosis is closely linked to MM. Amyloid light chain (AL) amyloidosis is the most common type of amyloidosis in the United States. Doctors may also refer to AL amyloidosis as primary amyloidosis.
The new approach, a collaboration among universities in Japan and Australia, looks for fragments of amyloid that end up in the blood stream. By assessing the ratios of types of amyloid fragment ...