Figure 2: Molecular and cellular changes in skin of wild-type and TNF-α –/– mice during tumor promotion. 'Tumor necrosis factor' might be considered an inappropriate name for a cytokine that ...

The Mouse Tumor Biology database (MTB) has been developed to provide electronic access to mouse tumor biology data. The primary focus of MTB is spontaneous and induced tumors in genetically ...

CSHL Professor Lloyd Trotman's lab has found that the pro-oxidant supplement menadione slows prostate cancer progression in mice. The supplement is a precursor to vitamin K, commonly found in ...

Researchers led by CSHL professor Lloyd Trotman’s lab have found that the pro-oxidant supplement menadione slows prostate cancer progression in mice. The supplement is a precursor to vitamin K ...

However, few studies have experimentally addressed the role of mtDNA levels in tumor progression. LUAD was induced by activation of the expression of a mutated Kras oncogene in the lungs of mice ...

The newly reported studies demonstrated that the antibodies, in a T cell engager format, can effectively kill cancer cells expressing relevant HER2 mutations both in vitro, and in a mouse ...

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell ...

A group of researchers from California looked at the impact of a culinary mushroom, white button mushroom extract, on the progression of prostate cancer in mice and patients. They propose that ...

The team then began testing menadione in mouse models bred to have human-like prostate cancer. They found that it slowed cancer progression through depletion of a lipid called PI(3)P that cancer ...

A new discovery at Cold Spring Harbor Laboratory (CSHL) points to a potentially groundbreaking solution. CSHL Professor Lloyd Trotman’s lab has found that the pro-oxidant supplement menadione slows ...