The selective advantage for the establishment and, more interestingly, the maintenance of heterogeneity in tumors is unclear. Our results indicate that tumors benefit collectively from protecting ...

In contrast, single-cell sequencing technology allows researchers to more fully characterize tissue heterogeneity, identify rare cell types, and dissect molecular mechanisms. The high level of ...

A number of studies have examined cellular heterogeneity in adipose tissue by using single-cell RNA sequencing (scRNA-seq).

Due to the tissue heterogeneity of most slide-mounted tissue sections, regions enriched for the cell types of interest are often dissected directly off these tissue sections. In one of the most ...

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell ...

Dr. Su Ryon Shin, Assistant Professor of Medicine, Brigham and Women’s Hospital, Harvard Medical School, gives a Chemical Engineering seminar titled, "Engineering nano-biomaterials for regenerative ...