Vijay K. Kuchroo, PhD, DVM, of the Gene Lay Institute of Immunology and Inflammation of Brigham and Women’s Hospital, Massachusetts General Hospital and Harvard Medical School and the Ann Romney ...
ILT3 activation leads to phosphorylation of phosphatases, SHP-1 and SHIP-1, to cause inhibition of NF-κB and p38/MAPK signaling pathways ... asthma by blocking Th2 cells.
T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response to environmental stimuli, these cells can differentiate into either TH1 ...