Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

One distinct feature of transcription factors is that they have DNA-binding domains that give them the ability to bind to specific sequences of DNA called enhancer or promoter sequences.

Thus, transcription-factor proteins can bind to several different ... suggesting they are for tissue-specific transcription and associated with nodule-specific function," said Ma.

Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, ...

Plant biologists like Aman Husbands at the University of Pennsylvania study a family of skilled subcontractors, known as the HD-ZIPIII transcription factors (TFs). These subcontractors are tasked ...