Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.

When gene regulation fails, or specific genes are altered ... colloquially known as the fruit fly, because of its simple genetics and the fact that its genetic elements are incredibly similar ...

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how ...

GET decodes the “grammar” of genes, revealing how they are activated or deactivated, ultimately influencing the proteins our ...

A new technology, mvGPT, is capable of precisely editing genes, activating gene expression, and repressing genes all at the same time.

the relatively simple mechanisms of gene expression in prokaryotic cells, as exemplified by the trp and lac operons, provide insight into several general principles involved in regulation in ...

Given the function of TFs, along with other mechanisms of eukaryotic gene regulation ... that separate complex and simple organisms from each other from a genetic standpoint.

However, the full spectrum of gene expression regulation associated with many ... changes in Alzheimer’s patients. “A simple way to explain it is if you have a longer transcript produced ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...

Along our journey, we shall reveal basic principles of gene regulation. We aim to exploit the new knowledge to help devise novel treatments of many diseases that stem from misregulated gene ...