The serotonin transporter (SERT) is a target for antidepressants and psychostimulants. Through a combination of non-canonical amino acid incorporation, protein purification, and spectroscopic ...

Sensorium Therapeutics Inc. has synthesized mesembrine derivatives acting as serotonin transporter (SERT) inhibitors reported to be useful for the treatment of anxiety, depression and stress disorders ...

Serotonin syndrome is a preventable, drug-related complication that results from increased brain-stem serotonin activity, usually precipitated by the use of one or more serotonergic drugs. Its ...