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Medscape
2 天
Clinical Significance of HIV Reverse-transcriptase Inhibitor-resistance Mutations
In addition, as NRTIs lack a 3'-hydroxyl group, they function as a chain terminator and inhibit reverse transcription. NRTI-resistance mutations & their mechanism of drug resistance M184V/I is the ...
Nature
4 个月
Human immunodeficiency virus type 1 reverse transcriptase and protease mutation search ...
Mutation frequency data ... Human immunodeficiency virus reverse transcriptase and protease sequence database. Nucleic Acids Res. 27, 348–352 (1999).
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