Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, ...

癌症，是一种由于体内细胞异常增殖引起的疾病。尽管 癌细胞 来源于自身，但它们依然可以成功躲避免疫系统的识别，逃脱其监视，进而失控生长。这种复杂的逃逸过程使得免疫系统在应对癌细胞时面临巨大挑战。而在过去十年间，研究者们开始关注肿瘤微环境（Tumor ...

作者发现，发现表达 CCL19 的成纤维网状细胞（FRC）在人类非小细胞肺癌中产生了相互连接的 T 细胞环境，包括三级淋巴结构和 T 细胞轨道。他们发现，FRC 在肿瘤内形成相互连接的网络，创造出专用的微环境壁龛，T 细胞聚集在那里有效地攻击 癌细胞 。

To explore how this environment is constructed, Lucas Onder at the Cantonal Hospital St. Gallen in Switzerland, and his colleagues investigated cells called fibroblastic reticular cells ...

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells ...

We recently discovered that these structures are essential for the establishment of reticular adhesions ... a multidisciplinary approach combining state-of-the-art techniques in cell biology, ...

11月19日Cell最新的研究“Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer”，发现成纤维网状细胞（Fibroblastic Reticular Cells ...