The most common nonfamilial forms of amyloidosis that involve the kidney are the AL (amyloid light chain) and AA (serum amyloid A) types. These two forms require different treatment strategies ...
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Of these, 5 had renal biopsy–confirmed renal AL amyloidosis, and 1 had LCDD. All 5 patients with AL amyloidosis had λ Bence Jones proteinuria. The only patient in our study with renal LCDD had ...
Renal protein deposits in AL amyloidosis and LCDD can cause both heavy albuminuria and Bence Jones proteinuria. Absent separate etiologies, this combined finding is rare and provides a clue to the ...
About NXC-201 NXC-201 is a sterically-optimized BCMA-targeted chimeric antigen receptor T (CAR-T) cell therapy. Initial data from Phase 1b/2 ex-U.S. study NEXICART-1 has demonstrated high complete ...
doctors may take a biopsy from an organ if they suspect amyloid may be causing heart or kidney problems. According to a 2021 study, AL amyloidosis may worsen the outlook for people with MM or ...