Our knowledge of RNA splicing is quite new. Nonetheless, because nearly all eukaryotes have introns and share mechanisms of RNA splicing, splicing itself must be quite ancient. Proponents of the ...

has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in the Journal of ...

Fungal tRNA Splicing as a Paradigm of RNA Repair – Intron-containing tRNAs are widespread ... (ii) developing a kinetic mechanism for the healing and sealing steps; (iii) highlighting distinctive ...

Specific RNA Sequences Are Required for Regulation ... Chen, M. & Manley, J. L. Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches.

The pathogenic mechanism is disruption of developmentally regulated RNA processing, primarily alternative splicing, in which failure to express adult splicing patterns causes primary features of the ...

Defects in RNA splicing or mutations can lead to a wide ... and RESCUE (RNA editing for specific C-to-U exchange) mechanisms.

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease ...

Why is this mechanism crucial for neuronal health ... higher levels of RTP801 can inhibit this complex and cause problems in RNA splicing and subsequent production of relevant proteins, such ...

When this mechanism is disrupted, the blueprints used by the cell to produce proteins are inaccurately edited through a process called splicing. The study, led by Goethe University Frankfurt ...

Group: Mechanisms and Regulation of pre-mRNA Splicing +44 20 7153 5086 0000-0002-7013-5504 Professor Vlad Pena is a structural biologist focusing on RNA splicing mechanisms and associated gene ...

Why is this mechanism crucial for neuronal health ... higher levels of RTP801 can inhibit this complex and cause problems in RNA splicing and subsequent production of relevant proteins, such ...

RNA-binding proteins (RBPs) play a crucial role in the post-transcriptional regulation of RNA expression, a finely tuned ...