上世纪90年代,美国科学家维克托·安布罗斯和加里·鲁夫坎找到了“生命指南”的关键——微小核糖核酸(微小RNA)及其在转录后基因调控中的作用 ...
The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story. However ...
记者10月10日从中山大学获悉,中山大学医学院施莽教授团队与阿里云李兆融团队在《细胞》杂志(Cell)发表的论文报告了全球范围的180个超群、16万余种的RNA病毒发现,大幅扩展了全球RNA病毒的多样性。 该研究将人工智能技术应用于病毒鉴定,发现了传统研究 ...
Ribonucleic acid (RNA) is a linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared ...
Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...
微小RNA(micro RNA)是一种很小的RNA分子。em,长度约为22nt(21-23nt)。micro RNA有几个特点: ①没有开放阅读框, 是非编码RNA,顾名思义就是 ...
Wave Life Sciences said today its alpha-1 antitrypsin deficiency (AATD) candidate WVE-006 succeeded in the first-ever clinical demonstration of RNA editing in humans by achieving positive proof-of ...
The remaining positions are occupied by carbon atoms, forming the backbone of important nucleobases in DNA and RNA. (Image: Public Domain) Types of Pyrimidines in Nucleic Acids There are three types ...
However, the less stable enol tautomer can also form and lead to mutations if incorporated into DNA during replication. The primary function of guanine is to store and transmit genetic information in ...
Researchers say they have successfully completed a trial of a personalised cancer vaccine that uses the same messenger-RNA technology as Covid jabs. The experimental vaccine, made by Moderna and ...
The aim is to identify essential residues involved in base flipping in the former and to determine the structural basis of multiple specificity in the latter. RNA and DNA Polymerases present ...
POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.