Department of Physiology, Division of Life Science, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan ...

(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1, 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B ...

The transduction of extracellular signals across the membrane to initiate complex cascades of molecular events regulates numerous ... We are also actively investigating the regulation of Syk tyrosine ...

They used a set of biochemical techniques to infer how the protein called Polo-like kinase 1 (PLK1) regulates the assembly of the machinery responsible for CENP-A reloading. A cascade of events ...

A cutting-edge study offers fresh insights into how roses defend themselves against the damaging fungus Botrytis cinerea, ...

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

PLK1 initiates the cascade of events by inducing a series of chemical changes (phosphorylation ... Reference: Conti D, Verza AE, Pesenti ME, et al. Role of protein kinase PLK1 in the epigenetic ...

They used a set of biochemical techniques to infer how the protein called polo-like kinase 1 (PLK1 ... PLK1 initiates the cascade of events by inducing a series of chemical changes ...

The discovery by Brown in 1993 that the calcium-sensing protein ... and activates a cascade of intracellular signals (such as the release of intracellular calcium, protein kinase C and ...

When bound to BMP6, the receptors recruit SMAD proteins and phosphorylation of SMAD1/5/8-SMAD4 complex mobilizes to the nucleus, activating the expression of hepcidin.