thus turning off expression of a gene. Positive regulation by TFs that are activators is common in eukaryotes. Considering the restrictive transcriptional ground state, it is logical that positive ...
The genome contains tens of thousands of genes. Like a gigantic orchestra, their interaction is the basis for all vital ...
Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...
Researchers hope the AI tool will aid in the development of cell-specific gene therapies to treat diseases such as cancer.
Their influence, however, can be either positive or negative ... but instead use one UAS sequence per gene, located upstream. Long-range regulation is thought to be indicative of the need for ...
A new technology, mvGPT, is capable of precisely editing genes, activating gene expression, and repressing genes all at the same time.