so the researchers studied the adenomatous polyposis coli (APC) gene, which causes the disease. The results showed the same congenital genetic mutation in canines as in human patients, meaning ...

Early diagnosis and prevention are important because colorectal cancer has a high incidence, but the cure rate is also quite ...

In addition, mutations are frequently detected in proteins such as p53, KRAS and APC (adenomatosis polyposis coli), which are intrinsically difficult to modulate with low-molecular-weight inhibitors.

Another high profile example is APC, which can refer to both the anaphase-promoting complex and the tumour suppressor adenomatous polyposis coli, both the subject of particularly intense study.

Dr. Albritton is a resident physician and Dr. Kingdom is Assistant Professor in the Department of Otolaryngology at Emory University School of Medicine, Atlanta, Ga. Albritton FD, Kingdom TT.