They may also be signalling molecules that act through interaction with specific receptors, as in peptide hormones and cytokines. A chimeric peptide designed to recruit immune cells has been shown ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

The Structural and Functional Diversity of Peptides Studies suggest that peptides may exhibit remarkable diversity in structure and function, which arises from variations in amino acid composition, ...

Scientists have found a way to help the body make more of an Ozempic-like fullness hormone to cut cravings and improve health.

G-protein–coupled receptors. For a long time, it remained a mystery how cells could sense their environment. Scientists knew that hormones such as adrenalin had powerful effects: increasing blood ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

A range of GLP-1 weight loss drugs are currently on the market. What are they, what do they do, and where are they available?

Peptides, small chains of amino acids ... Davies, M. J. (2023). Triple-hormone-receptor agonist Retatrutide for obesity — A phase 2 trial. *The New England Journal of Medicine*, 389(12 ...

One avenue for this ambition is cell receptors, which function like ignition slots on a cell, requiring keys—such as specific hormones ... Antigen-gated G protein-coupled Engineered Receptors ...