Nuclear receptors are receptors that bind to a ligand that has crossed the cell membrane, after which the ligand-bound receptor binds to DNA to regulate gene expression. These receptors are key ...
The sequence homology across the nuclear receptor superfamily indicates that these receptors evolved through divergent evolution 5, but gives no information about the role of ligands in the ...
Orphagen Pharmaceuticals Receives NIH Funding Award to Advance a Novel Drug for Inflammatory Bowel Disease Funding to support preclinical development of Orphagen’s lead IBD candidate, OR-812, a ...