Cargo molecules are transported through nuclear pore complexes (NPCs). Small molecules can pass by diffusion, but there is a permeability barrier for larger molecules, with a relative molecular ...

A herpes or HIV virus delivers its genome in the host cell nucleus through the nuclear pore complex. This delivery is ...

that a nuclear membrane and nuclear pore complexes similar to those of a real nucleus had formed around the injected DNA, and that the transport function necessary for a nucleus was sufficient.

ANA in PBC may be directed against the nuclear bodies (NB), the nuclear pore complex (NPC), centromeres, SSA/Ro, SSB/La, Scl-70, histones and other cellular nuclear constituents. [13–16] The ...

A study led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center discovered how the MX protein traps HIV-1 and herpes viruses by assembling decoy structures that mimic nuclear pore complexes.