Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Testing for natriuretic peptide markers, such as B-type natriuretic peptide (BNP) or N-terminal proBNP (NT-proBNP), has ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety ... of the beneficial effects of the body's own natriuretic peptides,” he continues.

Atrial natriuretic peptide (ANP) was the first natriuretic ... in the atria of the heart and activated when the atrial stretch receptors become stimulated in response to hypervolemia, increased ...