Blood mononuclear cells (HNC) are commonly isolated by Ficoll-Hypaque density centrifugation (FH) prior to monoclonal antibody staining and flow cytometric lymphocyte phenotype analysis.

Peripheral blood mononuclear cells (PBMCs) are stimulated by exercise and contribute not only to host defense, but also to growth, repair, and disease pathogenesis. Whether PBMC gene expression is ...

The following is a summary of “Tumor and Blood B Cell Abundance Outperforms Established Immune Checkpoint Blockade Response ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...

New in vitro preclinical data show CLN-978 induced similar T cell activation, target B cell depletion, and cytokine ...

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising ...

Individuals carrying this variant exhibited lower CCR5 expression and lower rates of HIV-1 infection in their cells. Before initiating ART, VNPs showed significantly lower total and intact HIV-1 DNA ...

Advanced therapy medicinal products (ATMPs) are pushing the boundaries of medicine, offering hope for previously untreatable ...

Phase 1 Basket Study for B Cell-mediated Autoimmune Diseases to Assess FT522 as Add-on to Standard-of-care Induction and Maintenance Regimens ...

Cullinan Therapeutics (CGEM) will present new preclinical data for CLN-978, its novel CD19xCD3 T cell engager. These data and the study schema ...