(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1, 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B ...

Kangbaida (Sichuan) Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) comprising a cereblon (CRBN) ligand coupled to a mitogen-activated protein kinase kinase kinase kinase ...

Department of Physiology, Division of Life Science, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan ...

The Company is currently developing neflamapimod, an investigational, orally administered small molecule brain penetrant that inhibits p38 mitogen-activated protein kinase alpha. Neflamapimod has the ...

My lab focuses on various functional characteristics of the pseudophosphatase map kinase serine/threonine binding protein (MK-STYX). MK-STYX is a novel protein included in the dual specificity mitogen ...

A cutting-edge study offers fresh insights into how roses defend themselves against the damaging fungus Botrytis cinerea, which causes severe losses in ornamental plants.

Lafleur E, Kapfer C, Joly V, Liu Y, Tebbji F, Daigle C, Gray-Mitsumune M, Cappadocia M, Nantel A and Matton DP 2015. The FRK1 mitogen-activated protein kinase kinase kinase (MAPKKK) from Solanum ...

Data from the AscenD-LB Phase 2a trial in DLB confirm recent scientific literature indicating that plasma glial fibrillary acid protein (GFAP) is ...

Topline data from the RewinD-LB Phase 2b study on track for December 2024 Detailed safety and efficacy data from RewinD-LB Phase 2b study to be featured in an oral presentation at the ILBDC conference ...

The NDA was submitted under the FDA's accelerated approval pathway, with Verastem requesting a priority review. If the FDA ...

DHA, PUFA, and SFA promote GnRH mRNA expression. Palmitate disrupts hypothalamic function in GnRH neurons by regulating spexin (SPX) and its receptors, galanin receptor 2 (GALR2) and galanin receptor ...