Defects in the oxidative phosphorylation (OXPHOS) system — the final biochemical pathway in the production of ATP — result in devastating, mainly multisystem diseases. The OXPHOS system is ...

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells ...

In humans, the main molecular energy carrier is adenosine triphosphate (ATP). It is critical for cellular functions all over ...

Its synthesis, which occurs in the mitochondria, through oxidative phosphorylation (OXPHOS) is a complex, multi-step process. When one or more of the elements of this process malfunction ...

Nematodes can sniff out trouble, kicking off a mitochondrial defense in the gut to fend off bacterial invaders.

Two major processes of this production (the Krebs cycle and oxidative phosphorylation) take place in the mitochondria. The ...

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function ...

Mitochondria are cellular organelles that produce most of the energy cells need to function. This energy is created in the form of ATP through a process known as oxidative phosphorylation.