Mitochondrial dynamics is particularly important to neurons, and defects result in neurodegenerative disease. Recent findings have sparked renewed appreciation for the remarkably dynamic nature of ...

These mitochondrial dynamics are vital to not only the function of mitochondria but also the health of cells overall. A cell is like a factory. Multiple departments must seamlessly work together ...

Jeremy Henley, Professor of Molecular Neuroscience in the School of Biochemistry, and corresponding author, added, ...

A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living ...

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a ...

Overcome the Challenge of Treating Unmet Medical Needs Caused by Mitochondrial Dysfunction The 2nd annual Mitochondria-Targeted Drug Development Summit returns as the only industry-led meeting ...

It offered promising results in activating parkin, a key protein in the brain responsible for tagging damaged proteins in mitochondria. Experts say the molecule’s ability to assist patients with ...

Several lines of evidence indicate that PINK1 can protect cells from different types of stress, including proteasomal inhibition, oxidative stress, mitochondrial blockers and apoptotic inducers.

Two main mechanisms have been implicated in the pathogenesis of PD as well as of most neurodegenerative diseases: mitochondrial dysfunction and accumulation of toxic proteins. Research on these ...