RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and 5’-PO 4 ends. RNA repair ...

The data shows that RNA interacts with a mitochondrial protein complex to trigger immune response pathways when viral RNA is ...

The Sixfold technology can access all of these different transport mechanisms, enabling delivery throughout the body. “There is a widely held view that most of the RNA circulating naturally in ...

New research has identified a critical fall-back mechanism used by the cells when the usual RNA editing process is switched off. Professor Carl Walkley heads the RNA Biology and Innate Immune ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...