Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

Mouse model reveals liver involvement in muscular dystrophy Date: October 24, 2024 Source: University of Illinois at Urbana-Champaign, News Bureau Summary: A new mouse model mimicking the liver ...

Lastly, reprogramming p16 Ink4a+ ECs through Kdr overexpression in a liver injury model significantly reduced fibrosis, ...

Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...

Based on hX4 binding points in the structure model, the researchers determined ... Ocaliva significantly reduced serum biomarkers of liver injury and reduced liver damage. Rats do not experience ...

Carisma Therapeutics Inc. (CARM) presented promising preclinical data on engineered macrophages for treating liver fibrosis at the ...