加州大学圣地亚哥分校George Sen团队在Immunity上发表了题为The transcription regulators ZNF750 and LSD1/KDM1A dampen inflammation on the skin’s surface by silencing pattern ...

The researchers were able to see that even when LSD1's enzymatic function was inhibited, its support ability could still maintain DNA methylation patterns necessary for cell differentiation and ...

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

In the fight against cancer, chimeric antigen receptor (CAR) T cell therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy. Science , 2024; 386 (6718) DOI: 10.1126/science.adl4492 Cite This Page : ...

More information: Xin Zhou et al, CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms, Nature Cancer (2024 ...

“As our precision-designed LSD1 and MALT1 inhibitors continue to progress towards the clinic, we are excited to share new preclinical data from both programmes,” said David Hallett, Ph.D ...

These are a type of white blood cell, called T cells, that move throughout your body to find and destroy bacteria, viruses, and other invading germs. Your test results help your doctor know how ...

According to many experts, we may soon find ourselves using fuel cells to generate electrical ... but as of now, you can't just fill up with hydrogen at a local gas station. Many people do have ...

Cells are the smallest unit of life and the building blocks for all organisms. Each component of a cell has its own function. Animal and plant cells differ and they have similarities. Nucleus ...