Serum TNF levels following LPS stimulation were also reduced using this gene silencing method. LPS injection is normally lethal, but treatment with siRNA-loaded particles protected mice by ...
Seeking an inflammatory factor causative of the onset of insulin resistance, obesity, and diabetes, we have identified bacterial lipopolysaccharide (LPS) as a triggering factor. We found that ...
Results: We found that at low nanomolar concentrations, treatment of rat primary mesencephalon neuron/glia cultures with CDDO-Me resulted in attenuated LPS-, TNF- or fibrillar amyloid beta 1-42 ...