该研究表明,吸入聚苯乙烯-微塑料(PS-MP)通过改变肺部菌群组成产生更多的脂多糖(LPS),促进小胶质细胞M1型极化,从而降低大脑认知功能,这为吸入微塑料引起神经损伤的机制提供了新见解,也为预防环境污染物的神经毒性提供了新思路。
以上研究揭示了同种异体干细胞移植后发生免疫排斥的表观调控新机制。不仅如此,通过生物信息学分析,该机制和靶点也广泛存在于其他种属和其他类型的细胞中。该通用型细胞构建策略的优势在于: ...
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