However, IL3-induced BAD phosphorylation is as sensitive to inhibition of MAP kinase kinase as it is to inhibition of PI(3)K (and hence of PKB/Akt), whereas GM-CSF-induced BAD phosphorylation is ...

Figure 4: The molecular mechanism by which phosphorylation inhibits GSK3. Figure 5: Several signalling pathways induce the inhibition of GSK3 by phosphorylating the same serine residue near the ...

Taking Out OGA. The rationale behind small-molecule OGA inhibition is that these drugs will decrease tau hyperphosphorylation ...