BAE: Bovine aortic endothelial; RHP: Recombinant human protein. NSAIDs variably inhibit prostaglandin H synthase (COX). COX-2 was cloned in 1991, and it was subsequently established that COX-1 ...

All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

Seven NSAIDs were compared in the analysis: four selective COX2 inhibitors (celecoxib, etoricoxib, rofecoxib and lumiracoxib) and three traditional NSAIDs (naproxen, ibuprofen and diclofenac).

Other NSAIDs do not have this effect. Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx ...

including that of aspirin and other NSAIDs. Information specifically about cyclo-oxygenase 2 inhibitors was not collected. Colorectal cancer was documented in 962 of the participants. Long-term ...