The fully human anti-TNF-α antibody adalimumab (Humira; Abbott) was approved by the FDA in 2007. This year, it has been joined by natalizumab (Tysabri; Elan/Biogen-Idec), a humanized antibody ...

An antibody drug can be a blockbuster. AbbVie’s Humira (adalimumab), which treats autoimmune conditions like Crohn’s disease, is the world’s best-selling drug, with sales of almost $20 ...

This month, five more Humira biosimilars are expected to launch besides Cyltezo. But none of the others have a therapeutic interchangeability classification. The originator monoclonal antibody ...

AbbVie executives said they have high hopes for Skyrizi and Rinvoq in the inflammatory bowel disease market after Humira ...

Winter founded Cambridge Antibody Technology in 1989, which first discovered adalimumab using phage display technology as part of a development partnership with BASF Pharma. After Abbott bought ...

The source of the mouse monoclonal antibody is a hybridoma that has been ... were previously obtained from a mouse immunized with Adalimumab F(ab’) 2 For long-term storage, it is recommended ...

Adalimumab trough levels of 4.0 mg/L or higher among patients with RA were linked to greater treatment response and achievement of remission.

AbbVie claimed FDA approval for its JAK inhibitor Rinvoq (upadacitinib) for rheumatoid arthritis on Friday, setting its price just a little below that of its antibody blockbuster Humira.

Paul Rhyne will describe how he combined all of the above mentioned ADA screening requirements into a single multiplex immunoassay for Humira® (adalimumab), a human monoclonal IgG1 antibody that binds ...

The timing of the Cordavis announcement was no accident. It came just as Humira, the highest grossing drug of all time, was set to start facing competition from biosimilars. Over its lifetime ...

Infliximab Remicaid® Chimeric monoclonal antibody iv. infusion ... administration only. ADM: Adalimumab; AUC 0-∞: Area under the plasma concentration-time curve from time zero to infinity ...