“The structural data of this study show the importance of the primary cilia of beta cells as important junctions for islet cell function,” Müller summarizes the results. In order to better ...

In both cases, the stress can eventually lead islet beta cells to stop producing insulin or die off. Stitzel and his colleagues wanted to know what genes and proteins were used by islet cells to ...

The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations.

Researchers have now discovered that DNA sequence changes known to increase a person's risk for diabetes are linked to how well pancreatic cells can handle two different kinds of molecular stress.

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

CASGEVY™ approved for the treatment of patients 12 years of age and older with sickle cell disease (SCD) and transfusion-dependent beta ...

Synthetic genes engineered to mimic how cells build tissues and structures. ScienceDaily . Retrieved November 6, 2024 from www.sciencedaily.com / releases / 2024 / 11 / 241104112240.htm ...

They suggest this work will be of special interest to researchers investigating the basic biology of liver function, as well as those investigating novel ... To investigate this, the team studied the ...